Effect of lagerstroemia speciosa L. [Jarut] leaves extracts on alloxan-induced diabetic rats

ABSTRACT

The hypoglycaemic effect of Lagerstroemia speciosa L. [locally known as Jaruf] leaves extracts]Ethanol, Chloroform, Hot water and 0.5% NaHCO[3] solution extracts] on chemically induced diabetic rats was investigated. Experimental result showed that, alloxan significantly [p0.00l] elevated the normal blood sugar level whereas ethanol, chloroform, hot water and 0.5% NaHCO[3] solution extracts depressed the alloxan-induced high blood sugar level about 30.91%, 35.51%, 43.25% and 45.55% respectively as compared to their respective diabetic controls. Thus, among the extracts, hot water extract and 0.5% NaHCO[3] solution extracts showed more blood sugar lowering activity than those of ethanol and chloroform extracts. These studies strongly suggest that various extracts of Lagerstroemia speciosa L. leaves possess prominent hypoglycaemic activity on experimental diabetes