Relationship between dietary pattern and cardiometabolic risk factors in women with PCOS

ABSTRACT

To identify a dietary pattern predictive of visceral adiposity index [VAI], using reduced rank regression, and to examine its associations with cardiometabolic risks in the PCOS women. This case-control study was conducted on 53 PCOS women and 167 age-matched healthy women from the population of Tehran Lipid and Glucose Study. Dietary intakes were collected using a semi-quantitative food frequency questionnaire. The associations of dietary pattern with cardiometabolic risks were investigated by Pearson's correlation and linear regression. In this study, a positively correlated VAI dietary pattern, characterized by high consumption of fried vegetables, vegetable oils [except for olive oil], fast foods and low consumption of dairy, and cruciferous vegetables was identified. The dietary pattern was correlated with triglycerides [rcontrols=0.32, rPCOS=0.41], triglycerides/HDL-C ratio [rcontrols=0.35, rPCOS=0.44] and HDL-C [rcontrols=-0.22, rPCOS=-0.26] in both groups. The pattern was also positively correlated with waist circumference, total cholesterol [TC], LDL-C and systolic blood pressure in the controls. After adjustment for age and BMI, dietary pattern was associated with triglycerides [Pcontrol=0.22, p=0.003; betaPCOS=0.48, P=0.001] and triglycerides/HDL-C ratio [Pcontrol= 0.23, P=0.002; betaPCOS= 0.52, P=0.001] in both groups. The dietary pattern was inversely associated with HDL-C in both groups, but the association was attenuated by adjusting for age and BMI in the PCOS group. High adherence to the dietary pattern was associated with cardiometaboiic risks in controls and to a lesser degree in the PCOS group