Mechanical post-conditioning in STEMI patients undergoing primary percutaneous coronary intervention
Journal of the Saudi Heart Association. 2015; 27 (3): 192-200
em Inglês
| IMEMR
| ID: emr-165690
ABSTRACT
Although early myocardial reperfusion via primary percutaneous coronary intervention [PCI] allows the preservation of left ventricular function and improves outcome, the acute restoration of blood flow may contribute to the pathophysiology of infarction, a complex phenomenon called reperfusion injury. First described in animal models of coronary obstruction, mechanical post-conditioning, a sequence of repetitive interruption of coronary blood flow applied immediately after reopening of the occluded vessel, was able to reduce the infarct size. However, evidence of its real benefit remains controversial. This review describes the mechanisms of post-conditioning action and the different protocols employed focusing on its impact on primary PCI outcome:
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
J. Saudi Heart Assoc.
Ano de publicação:
2015
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