Effect of noise and crowding related stress on serum level of cortisol ACTH, epinephrine and insulin in female albino rats

ABSTRACT

Noise and crowding are the most stressful factors for human beings.Study aimed to clarify their effect on cortisol, ACTH, epinephrine, insulin and the amelioration effectof Sulpiride. Thirty six female rats were divided into six groups [6/each]1- Rats served as control, 2- Rats treated with Sulpiride drug, 3- Rats exposed to noise [90db, 3hr. perday] for 45 days. 4- Rats exposed to noise and treated with sulpiride drug, 5- Rats exposed tocrowding. 6- Rats exposed to noise and treated with Sulpiride drug. Noise and crowding stresses caused a significant increase of cortisol, ACTH and epinephrinewhile there was a significant decrease in insulin hormone. Sulpiride drug ameliorated theseparameters. it is useful to use Sulpiride drug with people who are exposing to noise and crowdingstress