Evaluation of in vitro methods for the determination of sun protection factor of the homosalte standard sunscreen lotion

ABSTRACT

Exposure to the sunlight can have harmful effects on the human skin; such as, skincancers, hyperpigmentation and photoaging. Therefore, it is essential to use sunscreen productsto prevent these adverse effects. The photoprotection provided by a sunscreen product isassessed in terms of its sun protection factor [SPF]. There are in vivo and in vitro methods forthe SPF determination. In vivo methods have some problems; therefore, in vitro methods areused more often. In this study we compared 3 in vitro methods for the determination ofSPF of homosalte PDA standard sunscreen lotion. The SPF of the homosalte standard lotion by the method of solution in ethanol was8.23 +/- 0.13, by the method of solution in methanol method was 6.17 +/- 1.02 and by transpore tapemethod was 5.88 +/- 0.12. According to these results and statistical tests, transpore tape was the best method: