[Acanthosis nigricans, tripe palms and leser-trelat sign in patient with carcinoid tumor]

ABSTRACT

Acanthosis nigricans [AN], Tripe palm [TP] and sign of lesser trelat [LT] are rare dermatoses which are often seen with malignant conditions. Acanthosis nigricans occurs both on the skin and mucus membranes as velvety hyper pigmented lesions in the flexors and around the neck, or papillomatous and verrucous lesions on the lips and buccal mucosa. These para neoplastic dermatoses are generally linked with intra - abdominal malignancies, especially gastric adenocarcinomas and improvement of the associated dermatoses after treatment of the malignancy has been frequently observed, although it has also been observed with other malignancies. We report the case of a 44 year old woman who initially came to be treated for her mucocutaneous lesions, and with diagnosis of malignant AN was further studied for the initial malignancy and finally, her main malignancy was determined as carcinoid tumor