Hereditary ginfival fibromatosis: a 30 year follow up study in three genetations

ABSTRACT

Hereditary gingival fibromatosis [HGF] is a rare condition with undetermined etiology, thus is designated as idiopathic. Previous studies have revealed that the pattern of inheritance is autosomal dominant or [rarely] autosomal recessive. In our study a group of family members in three generations were followed for 30 years. This clinical and histological study was initiated by the extraction of remaining teeth and excision of the enlarged gingiva of the oldest member of the group. No recurrence happened after 30 years of follow-up. The other cases were operated twice during the primary and permanent dentition periods. After the second surgery, so far there has been no recurrence in any of the patients. In all cases the hyperplasia developed after the eruption of teeth and recurrence was observed after surgery in some of them who retained some teeth