Antibacterial effect of teucrium polium on the bacteria causing urinary tract infections

ABSTRACT

The present investigation was conducted to study the antibacterial effect of aqueous, ethanolic and ethyl acetate extracts of Teucrium polium plant on the bacteria isolated from urine samples of those with UTI and to compare it with the effect of commonly used antibiotics in treating UTIs. The antibiotic resistance of 147 strains of bacteria causing UTIs to the antibiotics selected through Kirby-Bauer disk diffusion method was determined. In the meantime, the aqueous, ethanolic and ethyl acetate extracts of T. polium plant were prepared. The antibacterial activity of these extracts was examined using Disk Diffusion Method. Finally, Minimum Inhibitory Concentration [MIC] and Minimum Bactericidal Concentration [MBC] of antibacterial were determined using serial dilution method. T. polium extracts were merely effective in enterococcus and pseudomonas bacteria. In general, the MIC rate of aqueous extract in enterococcus was 1.25-5 mg/ml. The MIC rate of ethanolic extract for enterococcus was calculated as 10 mg/ml. The MIC of aqueous and ethyl acetate extracts for pseudomonas bacteria were achieved as 5 and 20 mg/ml, respectively. The MBC contents of aqueous and ethyl acetate extracts of teucrium for pseudomonas bacteria was 10 mg/ml in aqueous and 20 mg/ml in ethyl acetate extracts. The MBC content of extracts for enterococcus bacteria were 10 mg/ml in aqueous extract and 20 mg/ml in ethanolic extract. T. polium extract can be effective in some bacteria causing urinary tract infection, especially enterococcus