Quality assessment of some paediatric Cotrimoxazole suspensions marketed in Bangladesh

ABSTRACT

This report includes the actual analytical studies on the marketed paediatric Cotrimoxazole suspensions manufactured by different companies. Ten brands of those suspensions obtained from different drug shops of the country were analyzed mostly according to B.P. method. Not only potency, but also other vital pharmaceutical parameters, such as appearance, weight/ml., pH, viscosity were taken into consideration, for making decision about the standard of the products. Because all these parameters collectively contribute to the total quality of the drug products. Among the ten brands, 7 were found substandard from the pharmaceutical point of view. Some necessary informations were also not mentioned in the package inserts