Determination of anti-enterobacterial common antigen in endemic hepatosplenomegaly

ABSTRACT

In this study anti-enterobacterial common [ECA] was determined in 60 patients with endemic hepatosplenomegaly, 43 with enterica and 82 apparently control group. It was found that the ECA was significantly increased [P less than 0.001] in chronic active hepatitis, while the schistosomal affection of the liver showed no increased difference either between the control or the enteric group inspite of the presence of the collateral circulation. It is concluded that the degree of damage of the Kupffer cells is responsible for the cases of bacteraemia rather than the degree of collateral circulation