Serum apolipoprotein B in childhood nephrotic syndrome

ABSTRACT

The study included fourteen patients suffering from nephrotic syndrome. They were 8 males [age range 3-13 ys] and 6 females [age range 3-5 ys] and 10 healthy controls. Serum total lipids for nephrotic patients was 1126.922 plus or minus 491.623 mg/d1 and that of the controls was 251.766 plus or minus 39.973 mg/d1. Such increase in patient group was statistically highly significant [p less than 0.0001]. Serum apoprotein B in nephrotic patients was 207.07 plus or minus 67.906 mg/d1 and that of controls was 100.1 plus or minus 15.934 mg/d1, this difference was statistically highly significant [P less than 0.001]. High level of apoprotein B is considered as a predictive factor and a good screening test for early detection of childhood atherosclerosis and ischemic heart disease