comparative study of bovine bone used alone and in combination with transforming growth factor-beta for the treatment of periodontal osseous defects in humans

ABSTRACT

Objectives: Transforming growth factor-betas [TGF[beta]s] are multifunctional growth factors with a broad range of biological activities in various cell types in many different tissues. The purpose of this study was to evaluate the treatment of intrabony defects with anorganic bovine bone mineral matrix combined with TGF[beta]-1 with the use of anorganic bovine bone alone