Neonatal idiopathic primary hypoparathyroidism: a rare cause of neonatal seizures

ABSTRACT

Etiology of neonatal seizures [NNS] is diverse and hypocalcemia is one of the treatable causes. Neonatal hypocalcemia [NHC] due to congenital hypoparathyroidism, either permanent or transient, is extremely rare. Its biochemical abnormalities include hypocalcemia, hyperphosphatemia and low levels of intact parathyroid hormone [PTH]. Isolated congenital hypoparathyroidism in which deficiency of PTH has no association with maternal, syndromic or endocrine defects is a very rare entity. We are reporting a case of a newborn who presented with seizures on the 5th day of life and later on investigations revealed hypocalcaemia due to isolated congenital hypoparathyroidism