Antiparasitic activity of silver and copper oxide nanoparticles against Entamoeba Histolytica and Cryptosporidium Parvum cysts
Journal of the Egyptian Society of Parasitology. 2015; 45 (3): 593-602
em Inglês
| IMEMR
| ID: emr-175057
ABSTRACT
Nanoparticles [NPs] have received more attention as antiparasitic agents. In the present study, silver and copper nanoparticles were synthesized and characterized using scanning electron microscopy [SEM], transmission electron microscope [TEM] and X-ray fluorescence [XRF]. The antiparasitic activity of Ag and CuO nanoparticles were tested against two of the most environmentally spread parasites in Egypt [Entamoeba histolytica and Cryptosporidium parvum]. The average sizes of synthesized Ag NPs and CuO NPs were 9 and 29 nm respectively and a significant reduction for cysts viability [p > 0.05] was observed for CuO NPs against E. histolytica cysts and Ag NPs against C. parvum oocysts. Moreover, LC[50]-3h of CuO NPs for E. histolytica and C. parvum were 0.13 and 0.72 mg/l, while Ag NPs recorded 0.34 and 0.54 mg/l respectively. Accordingly, these NPs could be suggested as a new nanoform agent for safe and effective treatment of E. histolytica and C. parvum parasites
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Prata
/
Cryptosporidium parvum
/
Cobre
/
Criptosporidiose
/
Entamoeba histolytica
/
Nanopartículas
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2015
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