Efficacy of magnesium sulphate in prevension of fits in severe pre-eclampsia

Objective: To evaluate the efficacy of magnesium sulphate as prophylactic agent in prevention of fits in severe pre-eclampsia

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Study Design: Interventional Quasi experimental study

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Setting: Department of Obstetrics and Gynaecology, Punjab Medical College and affiliated hospitals, Faisalabad

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Subject: Sixty patients of severe pre-eclampsia fulfilling the inclusion and exclusion criteria

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Main Outcome Measures: Occurrence of fit in case and control group, side effects of the drug like flushing, diminishing of reflexes, respiratory depression and hypotension in the case group

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Method: Sixty patients with severe pre-eclampsia were divided into two groups: Group A was taken as case and treated with MgSO[4], group B was taken as control and was not given MgSO[4]

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Results: Out of the 30 patients treated with MgSo[4] none [0%] had eclampsia in group A. In group B 4 [13.3%] patients developed eclampsia. Side effects of the drug were looked for in group A. Flushing was seen in 6 [20%] patients diminishing of reflexes was deserved in 1 [3.3%] patient

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Conclusion: MgSO[4] is an effective drug for prevention of fits in patient of severe preeclampsia