[Assessment of Foeniculum Vulgare L. methanolic extract effect on a model of Parkinson's disease induced by ICV injection of 6-hydroxydopamin in female rats, using behavioral tests]

ABSTRACT

Background and Aim: Oxidative stresses are involved in neuronal degeneration of substantia nigra and thereby induction of Parkinson's disease. It is reported that Foeniculum Vulgare L. can affect lactating and modulating dopaminergic system activity and antioxidant activity as well. In the present study, the effects of methanolic extract of Foeniculum Vulgare seeds on a Parkinson's disease model induced by ICV injection of 6-hydroxydopamin [6-OHDA] in female rats were investigated