Association of FTO rs9939609 SNP with obesity and obesity- associated phenotypes in a north Indian population

ABSTRACT

Objectives: Obesity is a common disorder that has a significant impact on morbidity and mortality. Twin and adoption studies support the genetic influence on variation of obesity, and the estimates of the heritability of body mass index [BMI] is significantly high [30 to 70%]. Variants in the fat mass and obesity-associated [FTO] gene have been associated with obesity and obesity-related phenotypes in different populations. The aim of this study was to examine the association of FTO rs9939609 with obesity and related phenotypes in North Indian subjects: