Thrombocytosis: analysis of 329 patients

ABSTRACT

To find out the nuquency of different clinical conditions causing thrombocytosis in hospitalized patient population. Cross sectional, descriptive study. Combined Military Hospital Attock, 1st Sept 2003 to 1[st] March 2004. All patients referred to haematology department for complete blood counts who had platelet count exceeding 400 x10[9] /L. Out of nine thousand patients, 329 [3.65%] revealed thrombocytosis. The Male to female ratio was 1.41, [48%] were adults, ana 52% were children. Platelet count ranged between 403 X10[9]/L and 1365 X10[9]/L In adults, iron deficiency [36%], infections [30%], infections concomitant with iron deficiency [13%], chronic inflammatory disorder [7%], clonal thrombocytosis [5%], haemorrhages [3%]; and in children infections concomitant with iron deficiency [36%], infections [26%], iron deficiency [18%], and acute gastro enteritis [6.5%] were the leading causes of thrombocytosis. Iron deficiency anaemia and infections are leading causes of thrombocytosis in our set up. Clonal thrombocytosis is seen in 5% of adult patients. Relative frequency of different conditions causing thrombocytosis varies with patient age