Comparative anti-glycation and alpha-glucosidase inhibition studies of microbial transformed compounds of dydrogesterone
Pakistan Journal of Pharmaceutical Sciences. 2015; 28 (2): 521-523
em Inglês
| IMEMR
| ID: emr-178149
ABSTRACT
Anti-glycation and alpha-glucosidase inhibition activities of microbial transformed compounds of dydrogesterone [1]; 20R-hydroxy-9 beta,10 alpha-pregna-4,6-diene-3-one [2], 17 beta-hydroxy-9 beta,10 alpha-androsta-4,6-diene-3-one [3] and 9 beta,10 alpha- androsta-4,6-diene-3,17-dione [4] were evaluated. Compounds 1 and 4 showed potent alpha-glucosidase inhibitory activities, while 2 and 3 were found to be weak inhibitors, whereas anti-glycation activities of 1-4 were not observed
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Glicosilação
/
Alfa-Glucosidases
/
Inibidores de Glicosídeo Hidrolases
Idioma:
Inglês
Revista:
Pak. J. Pharm. Sci.
Ano de publicação:
2015
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