GJB2 gene; Its contribution to genetic deafness?: a review

ABSTRACT

This article reviews the most prevalent sensory illness of mammals especially humans - Genetic Deafness or hearing loss [HL]. For genetic hearing loss more than 100 candidate genes have been discovered. The most common candidate gene of these all that is found all around the world is GJB2 gene. Different types of mutations are found in GJB2 gene. Some of these mutations are non-sense while some are sense mutations. This study is focus on mutation in GJB2 gene and its prevalence in different region of the world