Nanoceria attenuated high glucose-induced oxidative damage in hepg2 cells

ABSTRACT

Objective: Hyperglycemia, a common metabolic disorder in diabetes, can lead to oxidative damage. The use of antioxidants can benefit the control and prevention of diabetes side effects. This study aims to evaluate the effect of nanoceria particles, as an antioxidant, on glucose induced cytotoxicity, reactive oxygen species [ROS], lipid peroxidation [LPO] and glutathione [GSH] content in a human hepatocellular liver carcinoma cell line [HepG2] cell line