effect of combined administration of vitamins e and d3 on the demyelination and remyelination of rat's hippocampus

ABSTRACT

Background and purpose: Antioxidants and vitamin D3 are currently used for the treatment of neurodegenerative diseases although their mechanism of action is not well understood. The present study was conducted to investigate the effect of combined administration of vitamins D3 and E on demyelination, cell death and remyelination of rat hippocampus following the local ethidium bromide [EB] injection