effect of systemic administration of dbcamp on neural stem cells migration in eae model of multiple sclerosis

ABSTRACT

Background and Purpose: Novel strategies of MS try to stimulate endogenous neural stem cells for demyelination repair. Increased levels of cAMP potentiate the repair mechanisms in CNS by activating PKA or independently. In the present study, we investigated the effect of dbcAMP on neural stem cells migration in experimental autoimmune encephalomyelitis [EAE] model of MS