Immunoinformatics and Similarity Analysis of House Dust Mite Tropomyosin

ABSTRACT

Background: Dermatophagoides farinae and Dermatophagoides pteronyssinus are house dust mites [HDM] that they cause severe asthma and allergic symptoms. Tropomyosin protein plays an important role in mentioned immune and allergic reactions to HDMs. Here, tropomyosin protein from Dermatophagoides spp. was comprehensively screened in silico for its allergenicity, antigenicity and similarity/conservation.