Beta[2]-adrenergic receptor gene polymorphisms in normal and in patients with myocardial infarction in the eastern province of Saudi Arabia

ABSTRACT

Introduction: Single nucleotide polymorphisms [SNPs] of the beta[2]-adrenergic receptor [beta[2]-AR] gene have been implicated in the pathogenesis of cardiovascular diseases. This study evaluated two beta[2]-AR SNPs in association with myocardial infarction [MI], namely arginine-glycine [G16R] substitution at codon 16 and glutamine-glutamic [Q27E] substitution at condon 27