Association between polymorphisms of exon 12 and exon 24 of JHDM2A gene and male infertility
IJRM-International Journal of Reproductive Medicine. 2016; 14 (6): 389-396
em Inglês
| IMEMR
| ID: emr-182893
ABSTRACT
Background:
Some dynamic changes occurs during spermatogenesis such as histone removal and its replacement with transition nuclear protein and protamine. These proteins are required for packing and condensation of sperm chromatin. JHDM2A is a histone demethylase that directly binds to promoter regions of Tnp1 and Prm1 genes and controls their expression by removing H3K9 at their promoters
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
Int. J. Reprod. Med.
Ano de publicação:
2016
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