Association between HLA-E gene polymorphism and unexplained recurrent spontaneous abortion [RSA] in Iranian women
IJRM-International Journal of Reproductive Medicine. 2016; 14 (7): 477-482
em Inglês
| IMEMR
| ID: emr-182904
ABSTRACT
Background:
Human leukocyte antigen-E [HLA-E]is a non-classical major histocompatibility complex [MHC] class I antigens which expressed on extra villous cytotrophoblast, which interacts with NKG2A, is an inhibitory receptor on natural killer [NK] cells and leading to down regulation of immune response in the maternal-fetal interface and provides maternal immune tolerance of the fetus
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
Int. J. Reprod. Med.
Ano de publicação:
2016
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