Beta-galactosidase production by aspergillus niger ATCC 9142 using inexpensive substrates in solid-state fermentation: optimization by orthogonal arrays design

ABSTRACT

Background: Enzymatic hydrolysis of lactose is one of the most important biotechnological processes in the food industry, which is accomplished by enzyme beta-galactosidase [beta-gal, beta-D-galactoside galactohydrolase, EC 3.2.1.23], trivial called lactase. Orthogonal arrays design is an appropriate option for the optimization of biotechnological processes for the production of microbial enzymes