[Protective effect of Carthamus tinctorius L. extract on acetaminophen induced nephrotoxicity in mice]

ABSTRACT

Background and Objective: Acetaminophen is a commonly used analgesic and antipyretic agent which, in high doses, causes liver and kidney necrosis in man and animals. Carthamus tinctorius L. [Safflower] is a colorful and cheap plant that used often instead of saffron. In this study, protective effects of Carthamus tinctorius L. aqueous extract on acetaminophen induced nephrotoxicity in mice were investigated