Comparison of two anaesthetic induction techniques on blood cases and hemodynamics in cyanotic congenital heart disease

ABSTRACT

The optimal induction regimen for patients with cyanotic congenital heart disease [CCHD] should produce good oxygenation and maintain cardiovascular stability. This study was designed to evaluate and compare the haemodynamic and blood gas changes of isoflurane inhalation and intravenous ketamine induction techniques in children with CCHD. The study included 14 children with CCHD scheduled for cardiac surgery. Intravenous ketamine produced significant increase in systolic and diastolic pressure and heart rate only after intubation. Isoflurane produced significant reduction of systolic and diastolic blood pressure and increased heart rate after induction. Arterial oxygen tension [PaO2] and oxygen saturation [SaO2] showed significant increase after induction and intubation in isoflurane gp and mild increase after ketalar gp. It was concluded that both anaesthetic induction techniques are safe and effective in children with cyanotic congenital heart disease