Comparison of dexmedetomidine and clonidine as an adjuvant to lignocaine with adrenaline in infiltration anesthesia for tympanoplasty

ABSTRACT

Background: Adjuvants to local anesthetics enhance the quality and duration of analgesia. Dexmedetomidine, a potent alpha2-adrenoceptor agonist, is approximately eight times more selective towards the alpha2-adrenoceptor than clonidine. Dexmedetomidine was compared with clonidine in infiltration anesthesia when added to local anesthetic in infiltration anesthesia in tympanoplasty