Risk of osteoporosis and osteopenia in patients with prolonged use of proton pump inhibitors

ABSTRACT

Background and aim of the work Several studies suggest that proton pump inhibitors [PPIs] use may be involved in development and acceleration of osteoporosis. The aim of this study is to investigate the relationships between prolonged uses of PPIs in patients with gastro-esophageal reflux disease [GERD] and to reveal their possible role in development of osteopenia or osteoporosis with evaluation of different diagnostic tools which help in follow up of those patients