[One-step synthesis of anionic PEG-citrate G2 dendrimer and evaluation of its cytotoxicity in two cell lines]
Modares Journal of Medical Sciences, Pathobiology. 2015; 17 (4): 13-24
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| ID: emr-185158
ABSTRACT
Objective:
Dendrimers are three-dimensional nanostructures that have numerous applications in medicine, including drug delivery and imaging. Although anionic dendrimer polyethylene glycol-citrate has a high potential to increase solubility of waterinsoluble drugs and drug delivery, its multi-step synthesis procedure is time consuming. In addition, toxic substances such as dichloromethane are used in its synthesis procedure. In this study, we have developed a simple one-step synthesis method using green chemistry
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IMEMR (Mediterrâneo Oriental)
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Persa
Revista:
Modares J. Med. Sci., Pathobiol.
Ano de publicação:
2015
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