[Investigation of the dynamic culture medium on proliferation and differentiation of mesenchymal stem cells after culturing on electrospun PCL and PCL-nHA nanofibers]

ABSTRACT

Objective: More similarity to in vivo may help to increase the proliferation and differentiation of cells at in vitro culture. The present study has investigated the effect of a dynamic culture medium and nano hydroxyapatite [nHA] presence on proliferation and differentiation of mesenchymal stem cells [MSCs] to bone cells using electrospun polycaprolactone [PCL] scaffolds