[Study of foki and apai polymorphisms of vitamin D receptor gene in Iranian postmenopausal women with osteoporosis]

ABSTRACT

Background and Objectives: Osteoporosis along with decreased bone density can lead to bone structure loss which increases the risk of fractures. Recent identification of genetic factors impels researchers to assess association of genetic variations with osteoporosis. The aim of this study was to evaluate the relationship between FokI and ApaI polymorphisms of vitamin D receptor [VDR] gene and serum calcium level, serum 25-OH vitamin D level and osteoporosis in Iranian postmenopausal women