[Histomorphometric study of examination of the aqueous extract effect of grape [vitis vinifera] on wound healing diabetic male wistar rats]

Introduction and Aims: In the event of damage to the skin, the epidermis of which goes to the disintegration of the body, is a wound that is common in diabetics. The purpose of this study was to evaluate the effect of aqueous extract of grape [Vitis Vinifera] on wound healing in diabetic Wistar rat

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Materials and Methods: In this study 48 male Wistar rats were divided into 4 groups [control, sham, experimental 1, empirical 2] were tested. The extra pawn injured area of 3 cm to the left of the spine created. Extract-treated group compared to one in three [aqueous extract + eucerin] received. Wound healing was examined microscopically during 21 days

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Results: Wound healing in group that became diabetes using streptozocin [the diabetic rats], showed late recovery compared to normal wound healing in normal groups and wound healing in experimental groups treated with aqueous extract of grape was accelerated compared control group

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Conclusion: The results showed that the aqueous extract of grape skin accelerate wound healing in normal and diabetic samples