Relevance of helicobacter pylori plasticity and cagPAI regions known genes to gastric and duedenal ulcers in Iran

ABSTRACT

Background: Helicobacter pylori [H. pylori] is the main cause of gastroduodenal diseases, such as chronic atrophic gastritis, gastric ulcer [GU], and duodenal ulcer [DU]. There is a close relationship between H. or/-specific factors and different gastroduodenal diseases. The aim of the present study was to clarify the roles of the plasticity region genes [jhp0940, jhp0945, and jhp0947] and the known genes of cagPAI [cagA and cage] in relation to GU and DU diseases