Prognostic importance of C-KIT mutations in core binding factor acute myeloid leukemia: a systematic review
Hematology, Oncology and Stem Cell Therapy. 2017; 10 (1): 1-7
em Inglês
| IMEMR
| ID: emr-186589
ABSTRACT
Acute myeloid leukemia [AML] is defined as leukemic blast reproduction in bone marrow. Chromosomal abnormalities form different subgroups with joint clinical specifications and results. t[8;21][q22;q22] and inv[16][p13;q22] form core binding factor- AML [CBF-AML]. c-kit mutation activation occurs in 12.8-46.1% of adults with CBF leukemia. These mutations occur in 20-25% of t[8;21] and 30% of inv[16] cases
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Índice:
IMEMR (Mediterrâneo Oriental)
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Idioma:
Inglês
Revista:
Hematol. Oncol. Stem Cell Ther.
Ano de publicação:
2017
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