Conjugates of B-cells and platelet microparticles in the human peripheral blood

ABSTRACT

Background: Activated platelets shed microparticles [MPs] in vivo and certainly in vitro under storage. Like platelets, platelet-derived MPs contribute to hemostatic and inflammatory responses. We sought to determine the interactions between platelet MPs and peripheral B lymphocytes in the healthy blood circulation to propose a possible role for platelet MPs in the functioning of B cells