Cell membrane transferrin receptor expression [TER] in bilharzial bladder cancer

ABSTRACT

This work was carried out upon tissue specimens obtained from 22 patients with non malignant urologic lesion and 34 patients with bladder carcinoma. All were subjected to transferrin receptor [TFR] identification on the cell membrane In all non malignant cases there was negative expression of [TFR] while it was manifested in 94% of malignant cases [32 out of 34]. In two of the malignant cases [6%] there was negative expression of [TFR] as both cases were verrucous carcinoma because of the very low grade and degree of the malignant process in such cases can be expected