Amphotericin B induced hypokalemia in a diabetic patient with rhino-orbitocerebral mucormycosis
Anaesthesia, Pain and Intensive Care. 2017; 21 (1): 90-93
em Inglês
| IMEMR
| ID: emr-187468
ABSTRACT
Rhino-orbito-cerebral mucormycosis is an aggressive and potentially lethal invasive fungal infection. Surgical debridement and amphotericin B remain the mainstay of treatment, however, associated side effects of amphotericin B like nephrotoxicity, hypokalemia, hypertension and arrhythmias need to be addressed. We discuss the anesthetic management of a 47 year old male with uncontrolled diabetes diagnosed with left sinoorbital mucormycosis posted for surgical debridement. The patient received amphotericin B and insulin preoperatively. Nephrotoxicity due to amphotericin B led to hypokalemia in this patient. We also discuss the role of liposomal formulation in preventing hypokalemia and other side effects associated with use of amphotericin
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Doenças Orbitárias
/
Doenças Nasais
/
Infecções Fúngicas do Sistema Nervoso Central
/
Complicações do Diabetes
/
Hipopotassemia
/
Mucormicose
Tipo de estudo:
Relato de Casos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Anaesth. Pain Intensive Care
Ano de publicação:
2017
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