Using beta-cyclodextrin and Arabic gum as wall materials for encapsulation of saffron essential oil
IJPR-Iranian Journal of Pharmaceutical Research. 2017; 16 (1): 93-102
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| ID: emr-187950
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EMRO
Saffron essential oil has a pleasant aroma and medicinal activities. However, it is sensible into the environmental condition. Therefore, it should be protected against unwanted changes during storage or processing. Encapsulation is introduced as a process by which liable materials are protected from unwanted changes. In the present study, different ratios [0:100, 25:75, 50:50, 75:25, and 100:0] of beta-cyclodextrin [beta-CD] and arabic gum [GA] were used as wall martial for encapsulation saffron essential oil. In order to calculate of loading capacity [LC] and encapsulation efficiency [EE], and release [RE], safranal was determined as indicator of saffron essential oil using GC. According to the results, the highest LC and EE were related to the mixture of beta-CD/GA at a 75:25 ratio. In contrast, the lowest encapsulate hygroscopicity [EH] and RE were observed when only beta-CD was applied as wall material [P=0.05]. Comparing the differential scanning calorimetry [DSC] thermograms of the control and encapsulate of beta-CD/GA [75:25] confirmed encapsulation of saffron essential oil. Scanning electron microscopy [SEM] images with high magnifications showed the rhombic structure that partially coated by GA. The mixture of beta-CD/GA at a 75:25 ratio can be recommended for saffron essential oil encapsulation
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Índice:
IMEMR
Idioma:
En
Revista:
Iran. J. Pharm. Res.
Ano de publicação:
2017