Synthesis and Antimicrobial evaluation of oxadiazolylbenzotriazole derivatives

ABSTRACT

Three novel series of 1H-benzotriazole derivatives containing oxadiazole or oxadiazoline moiety were synthesized, namely; 1-[3- substituted methyl 1, 3, 4-oxadiazole-2[3H]-thion-5-yl]methyl 1-H- benzotriazoles, 1-[2-substituted amino-1, 3, 4-oxadiazol-5-yl] methyl-1H-benzotriazoles and 1-[3-acetyl-5aryl-2, 3-dihydro-1, 3, 4- oxadiazol-2-yl] methyl-1H-benzotriazoles. The antimicrobial testing of the final compounds as well as the key intermediates was performed