Role of rebamipide and or pantoprazole in preventing dexamethasone induced gastritis in senile male albino rats

ABSTRACT

Aim of the work gastritis is the inflammation of the lining of the stomach .It is caused by many factors like infection by Helicobacter pylori, drug induced such as aspirin, Non-Steroidal Anti-Inflammatory Drugs [NSAIDs], corticosteroids and alcohol consumption. Pantoprazole prevents HCL formation by blocking proton pumps in parietal cells of the stomach leading to stoppage of pepsinogen enzyme activation