[Anti-proliferative and apoptotic effects of Lovastatin on K562 Erthromyloidy cancer cell line]
Journal of Gorgan University of Medical Sciences. 2017; 18 (4): 52-59
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| ID: emr-189606
ABSTRACT
Background and Objective:
Lovastatin is a HMG-CoA reductase inhibitor and used for the treatment of hypercholesterolemia. Inhibition of HMG-CoA reductase results in inhibiting the activity of the Ras proto-oncogene that has mutations in most cancers. This study was done to determine the Anti-proliferative and apoptotic effects of Lovastatin on K562 Erthromyloidy cancer cell line
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Apoptose
/
Células K562
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Linhagem Celular Tumoral
Idioma:
Persa
Revista:
J. Gorgan Univ. Med. Sci.
Ano de publicação:
2017
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