[Increased risk of gastric cancer in the CC genotype -31C/G polymorphism in Survivin gene promoter]
Journal of Gorgan University of Medical Sciences. 2017; 18 (4): 32-37
em Persa
| IMEMR
| ID: emr-189609
ABSTRACT
Background and Objective:
Gastric cancer is the most common cancers worldwide. The survivin gene which encodes an apoptosis protein inhibitor plays an important role in maintenance and integrity of the gastric mucosa. The gene is necessary for the normal physiologic function of the stomach, but its expression increases in gastric cancer. Regarding with the role of polymorphisms of the promoter region in genes expression, this study was done to determine the association of single-nucleotide polymorphism [rs9904341] -31C/G in promoter survivin gene with risk of gastric cancers
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Polimorfismo de Fragmento de Restrição
/
Estudos de Casos e Controles
/
Reação em Cadeia da Polimerase
/
Risco
/
Polimorfismo de Nucleotídeo Único
/
Proteínas Inibidoras de Apoptose
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Persa
Revista:
J. Gorgan Univ. Med. Sci.
Ano de publicação:
2017
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