Cell Journal [Yakhteh]. 2018; 19 (4): 569-577
em Inglês
| IMEMR
| ID: emr-189847
ABSTRACT
Objective:
aggregation of the TAU proteins in the form of neurofibrillary tangles [NFTs] in the brain is a common risk factor in tauopathies including Alzheimer's disease [AD]. Several strategies have been implemented to target NFTs, among which chaperones, which facilitate the proper folding of proteins, appear to hold great promise in effectively inhibiting TAU polymerization. The aim of this study was to analyze the impact of the chaperone Artemin on TAU aggregation in vitro
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
Cell J. [Yakhteh]
Ano de publicação:
2018
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