Efficacy of intrauterine injection of granulocyte colony stimulating factor [G-CSF] on treatment of unexplained recurrent miscarriage: a pilot RCT study

ABSTRACT

Background: Endometrium undergoes several changes in structure and cellular composition during pregnancy. Granulocyte Colony-stimulating Factor [GCS-F] is an important cytokine with critical role in embryo implantation and pregnancy. The aim of the present study was to evaluate the impact of intrauterine injection of G-CSF in patients who suffer from unexplained recurrent miscarriage [RM]