In vitro cysteine reactivates organophosphate insecticide dichlorvos-inhibited human cholinesterases
SQUMJ-Sultan Qaboos University Medical Journal. 2017; 17 (3): 293-300
em Inglês
| IMEMR
| ID: emr-190237
ABSTRACT
Objectives:
Organophosphate [OP] pesticides inhibit both red blood cell [RBC] and plasma cholinesterases [ChEs]. Oximes, especially pralidoxime [2-PAM], are widely used as antidotes to treat OP poisoning. In addition, N-acetylcysteine [NAC] is sometimes used as an adjuvant antidote. The current study aimed to assess the feasibility of using NAC as a single therapeutic agent for OP poisoning in comparison to in vitro 2-PAM
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
Sultan Qaboos Univ. Med. J.
Ano de publicação:
2017
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