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In vitro cysteine reactivates organophosphate insecticide dichlorvos-inhibited human cholinesterases
SQUMJ-Sultan Qaboos University Medical Journal. 2017; 17 (3): 293-300
em Inglês | IMEMR | ID: emr-190237
ABSTRACT

Objectives:

Organophosphate [OP] pesticides inhibit both red blood cell [RBC] and plasma cholinesterases [ChEs]. Oximes, especially pralidoxime [2-PAM], are widely used as antidotes to treat OP poisoning. In addition, N-acetylcysteine [NAC] is sometimes used as an adjuvant antidote. The current study aimed to assess the feasibility of using NAC as a single therapeutic agent for OP poisoning in comparison to in vitro 2-PAM
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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Sultan Qaboos Univ. Med. J. Ano de publicação: 2017

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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Sultan Qaboos Univ. Med. J. Ano de publicação: 2017