[Mutation spectrum of beta-thalassemia among carriers in Birjand and Amirabad village]

ABSTRACT

Background and Aim: Thalassemia is considered as the most important monogenic disorders around the world. So far, about 60 mutations of this type have been reported in Iranian patients. Comparison between different provinces of the country reveals that the dispersion of the mutations is significantly various with respect to their types and frequencies. The current study aimed at assessing prevalent molecular mutations in beta Thalassemia carriers in Birjand and Amirabad at the suburb of the city